2018
Kahounová, Zuzana; Slabáková, Eva; Binó, Lucia; Remšík, Ján; Fedr, Radek; Bouchal, Jan; Kurfűrstová, Daniela; Vrtěl, Radek; Študent, Vladimír; Jurečková, Lucie; Porokh, Volodymyr; Hampl, Aleš; Souček, Karel
Generation of human iPSCs from human prostate cancer-associated fibroblasts IBPi002-A. Journal Article
In: Stem cell research, vol. 33, pp. 255–259, 2018, ISSN: 1876-7753 1873-5061, (Place: England).
Abstract | Links | BibTeX | Tags: Aged, Cancer-Associated Fibroblasts/*metabolism, Fibroblasts/*metabolism, Humans, Induced Pluripotent Stem Cells/*metabolism, Male, Prostatic Neoplasms/*genetics
@article{kahounova_generation_2018,
title = {Generation of human iPSCs from human prostate cancer-associated fibroblasts IBPi002-A.},
author = {Zuzana Kahounová and Eva Slabáková and Lucia Binó and Ján Remšík and Radek Fedr and Jan Bouchal and Daniela Kurfűrstová and Radek Vrtěl and Vladimír Študent and Lucie Jurečková and Volodymyr Porokh and Aleš Hampl and Karel Souček},
doi = {10.1016/j.scr.2018.11.006},
issn = {1876-7753 1873-5061},
year = {2018},
date = {2018-12-01},
journal = {Stem cell research},
volume = {33},
pages = {255–259},
abstract = {A human induced pluripotent stem cell line was generated from cancer-associated fibroblasts of a 68-years old patient with diagnosed prostate adenocarcinoma (PCa). The fibroblast cell line was reprogrammed with Epi5™ Episomal iPSC Reprogramming Kit. Pluripotency of the derived transgene-free iPS cell line was confirmed both in vitro by detecting expression of factors of pluripotency on a single-cell level, and also in vivo using teratoma formation assay. This new iPS cell line may be used for differentiation into different prostate-specific cell types in differentiation studies.},
note = {Place: England},
keywords = {Aged, Cancer-Associated Fibroblasts/*metabolism, Fibroblasts/*metabolism, Humans, Induced Pluripotent Stem Cells/*metabolism, Male, Prostatic Neoplasms/*genetics},
pubstate = {published},
tppubtype = {article}
}
A human induced pluripotent stem cell line was generated from cancer-associated fibroblasts of a 68-years old patient with diagnosed prostate adenocarcinoma (PCa). The fibroblast cell line was reprogrammed with Epi5™ Episomal iPSC Reprogramming Kit. Pluripotency of the derived transgene-free iPS cell line was confirmed both in vitro by detecting expression of factors of pluripotency on a single-cell level, and also in vivo using teratoma formation assay. This new iPS cell line may be used for differentiation into different prostate-specific cell types in differentiation studies.